Vitamin A Metabolite, All-trans-retinoic Acid, Mediates Alternative Splicing of Protein Kinase C δVIII (PKCδVIII) Isoform via Splicing Factor SC35

Vitamin A metabolite, all-trans-retinoic acid (RA), induces cell growth, differentiation, and apoptosis and has an emerging role in gene regulation and alternative splicing events. Protein kinase Cδ (PKCδ), a serine/threonine kinase, has a role in cell proliferation, differentiation, and apoptosis....

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Autores principales: Apostolatos, Hercules, Apostolatos, André, Vickers, Timothy, Watson, James E., Song, Shijie, Vale, Fernando, Cooper, Denise R., Sanchez-Ramos, Juan, Patel, Niketa A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923993/
https://ncbi.nlm.nih.gov/pubmed/20547768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.100735
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