Discovery and Characterization of HemQ: AN ESSENTIAL HEME BIOSYNTHETIC PATHWAY COMPONENT

Here we identify a previously undescribed protein, HemQ, that is required for heme synthesis in Gram-positive bacteria. We have characterized HemQ from Bacillus subtilis and a number of Actinobacteria. HemQ is a multimeric heme-binding protein. Spectroscopic studies indicate that this heme is high s...

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Bibliografiske detaljer
Main Authors: Dailey, Tamara A., Boynton, Tye O., Albetel, Angela-Nadia, Gerdes, Svetlana, Johnson, Michael K., Dailey, Harry A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923992/
https://ncbi.nlm.nih.gov/pubmed/20543190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142604
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