CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form of Candida albicans

The scaffold protein CARD9 plays an essential role in anti-fungus immunity and is implicated in mediating Dectin-1/Syk-induced NF-κB activation in response to Candida albicans infection. However, the molecular mechanism by which CARD9 mediates C. albicans-induced NF-κB activation is not fully charac...

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Detalhes bibliográficos
Main Authors: Bi, Liangkuan, Gojestani, Sara, Wu, Weihui, Hsu, Yen-Michael S., Zhu, Jiayuan, Ariizumi, Kiyoshi, Lin, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923990/
https://ncbi.nlm.nih.gov/pubmed/20538615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.131300
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