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Exposure to naphthalene induces naphthyl-keratin adducts in human epidermis in vitro and in vivo

We observed naphthyl-keratin adducts and dose-related metabolic enzyme induction at the mRNA level in reconstructed human epidermis in vitro after exposure to naphthalene. Immunofluorescence detection of 2-naphthyl-keratin-1 adducts confirmed the metabolism of naphthalene and adduction of keratin. W...

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Detalhes bibliográficos
Main Authors: Kang-Sickel, Juei-chuan C., Stober, Vandy P., French, John E., Nylander-French, Leena A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923669/
https://ncbi.nlm.nih.gov/pubmed/20500019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1354750X.2010.485700
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