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Leptin-induced Growth Stimulation of Breast Cancer Cells Involves Recruitment of Histone Acetyltransferases and Mediator Complex to CYCLIN D1 Promoter via Activation of Stat3

Numerous epidemiological studies documented that obesity is a risk factor for breast cancer development in postmenopausal women. Leptin, the key player in the regulation of energy balance and body weight control also acts as a growth factor on certain organs in both normal and disease state. In this...

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Autori principali: Saxena, Neeraj K., Vertino, Paula M., Anania, Frank A., Sharma, Dipali
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923657/
https://ncbi.nlm.nih.gov/pubmed/17344214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609798200
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