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Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator

Human autoimmune regulator (AIRE) functions to control thymic expression of tissue-specific antigens via sequence-specific histone H3 recognition by its plant homeodomain (PHD) finger. Mutations in the AIRE PHD finger have been linked to autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy...

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Detalhes bibliográficos
Main Authors: Chakravarty, Suvobrata, Zeng, Lei, Zhou, Ming-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923636/
https://ncbi.nlm.nih.gov/pubmed/19446523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.02.017
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