Unique DNA Repair Gene Variations and Potential Associations with the Primary Antibody Deficiency Syndromes IgAD and CVID

BACKGROUND: Despite considerable effort, the genetic factors responsible for >90% of the antibody deficiency syndromes IgAD and CVID remain elusive. To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination. This process is initiated by AID-catalyzed d...

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Bibliographische Detailangaben
Hauptverfasser: Offer, Steven M., Pan-Hammarström, Qiang, Hammarström, Lennart, Harris, Reuben S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923613/
https://ncbi.nlm.nih.gov/pubmed/20805886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012260
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