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Apparent Non-Canonical Trans-Splicing Is Generated by Reverse Transcriptase In Vitro

BACKGROUND: Trans-splicing, the in vivo joining of two independently transcribed RNA molecules, is well characterized in lower eukaryotes, but was long thought absent from metazoans. However, recent bioinformatic analyses of EST sequences suggested widespread trans-splicing in mammals. These apparen...

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Detalhes bibliográficos
Main Authors: Houseley, Jonathan, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923612/
https://ncbi.nlm.nih.gov/pubmed/20805885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012271
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