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Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis

We present a novel microfabricated platform to culture cells within arrays of micrometer-scale three-dimensional (3D) extracellular matrix scaffolds (microgels). These microscale cultures eliminate diffusion barriers that are intrinsic to traditional 3D culture systems (macrogels) and enable uniform...

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Hlavní autoři: Raghavan, Srivatsan, Shen, Colette J., Desai, Ravi A., Sniadecki, Nathan J., Nelson, Celeste M., Chen, Christopher S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923566/
https://ncbi.nlm.nih.gov/pubmed/20682635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.055079
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