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Opioid antagonism enhances marijuana's effects in heavy marijuana smokers

RATIONALE AND OBJECTIVE: Studies in laboratory animals strongly suggest reciprocal modulation of the opioidergic and endocannabinoid systems, a relationship that has not been demonstrated in humans. This study sought to clarify this interaction by assessing how a range of naltrexone doses altered th...

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Bibliographic Details
Main Authors: Cooper, Ziva D., Haney, Margaret
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923559/
https://ncbi.nlm.nih.gov/pubmed/20490465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1875-y
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