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Memory T cells need CD28 costimulation to remember

The activation and expansion of naïve T cells require costimulatory signals provided by CD28 and TNF family members. In contrast, for many years it was believed that memory T cells do not require CD28 costimulation for expansion during secondary responses. This was based on in vitro experiments that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Boesteanu, Alina C., Katsikis, Peter D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923542/
https://ncbi.nlm.nih.gov/pubmed/19268606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2009.02.005
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