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Memory T cells need CD28 costimulation to remember
The activation and expansion of naïve T cells require costimulatory signals provided by CD28 and TNF family members. In contrast, for many years it was believed that memory T cells do not require CD28 costimulation for expansion during secondary responses. This was based on in vitro experiments that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923542/ https://ncbi.nlm.nih.gov/pubmed/19268606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2009.02.005 |
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