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Effect of ligand binding on human d-amino acid oxidase: Implications for the development of new drugs for schizophrenia treatment
In human brain the flavoprotein d-amino acid oxidase (hDAAO) is responsible for the degradation of the neuromodulator d-serine, an important effector of NMDA-receptor mediated neurotransmission. Experimental evidence supports the concept that d-serine concentration increase by hDAAO inhibition may r...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923503/ https://ncbi.nlm.nih.gov/pubmed/20521334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.429 |
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