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Foxp3(+) CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection

Regulatory Foxp3(+) CD4 T cells (Tregs) prevent spontaneous inflammation in the lungs, inhibit allergic and asthmatic responses, and contribute to tolerance to inhaled allergens. Additionally, Tregs have previously been shown to suppress the CD8 T cell response during persistent virus infections. Ho...

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Autori principali: Fulton, Ross B., Meyerholz, David K., Varga, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923480/
https://ncbi.nlm.nih.gov/pubmed/20639494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000423
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