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Temperature-induced unfolding of epidermal growth factor (EGF): insight from molecular dynamics simulation
Thermal disruption of protein structure and function is a potentially powerful therapeutic vehicle. With the emerging nanoparticle-targeting and femtosecond laser technology, it is possible to deliver heating locally to specific molecules. It is therefore important to understand how fast a protein c...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923262/ https://ncbi.nlm.nih.gov/pubmed/20466569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2010.03.011 |
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