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Identify Interaction Genes in Genome-Wide Association Studies Using a Model-Based Two-Stage Approach

In this paper, we propose a two-stage approach based on seventeen biological plausible models to search for two-locus combinations that have significant joint effects on the disease status in genome-wide association (GWA) studies. In the two-stage analyses, we only test two-locus joint effects of SN...

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Hlavní autoři: Zhang, Zhaogong, Niu, Adan, Sha, Qiuying
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923239/
https://ncbi.nlm.nih.gov/pubmed/20636464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00594.x
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