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Expression of HPV16 E5 Produces Enlarged Nuclei and Polyploidy through Endoreplication

Anogenital cancers and head and neck cancers are causally-associated with infection by high-risk human papillomavirus (HPV). The mechanism by which high-risk HPVs contribute to oncogenesis is poorly understood. HPV16 encodes three genes (HPV16 E5, E6, and E7) that can transform cells when expressed...

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Bibliografiset tiedot
Päätekijät: Hu, Lulin, Potapova, Tamara A., Li, Shibo, Rankin, Susannah, Gorbsky, Gary J., Angeletti, Peter C., Ceresa, Brian P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923234/
https://ncbi.nlm.nih.gov/pubmed/20605566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.06.025
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