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Astrocytic gap junctional communication is reduced in amyloid-β-treated cultured astrocytes, but not in Alzheimer's disease transgenic mice

Alzheimer's disease is characterized by accumulation of amyloid deposits in brain, progressive cognitive deficits and reduced glucose utilization. Many consequences of the disease are attributed to neuronal dysfunction, but roles of astrocytes in its pathogenesis are not well understood. Astroc...

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Bibliographic Details
Main Authors: Cruz, Nancy F, Ball, Kelly K, Dienel, Gerald A
Format: Artigo
Language:Inglês
Published: American Society for Neurochemistry 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922840/
https://ncbi.nlm.nih.gov/pubmed/20730033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20100017
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