De Novo Truncating FUS Gene Mutation as a Cause of Sporadic Amyotrophic Lateral Sclerosis

Mutations in the gene encoding fused in sarcoma (FUS) were recently identified as a novel cause of amyotrophic lateral sclerosis (ALS), emphasizing the genetic heterogeneity of ALS. We sequenced the genes encoding superoxide dismutase (SOD1), TAR DNA-binding protein 43 (TARDBP) and FUS in 99 sporadi...

Full description

Saved in:
Bibliographic Details
Main Authors: DeJesus-Hernandez, Mariely, Kocerha, Jannet, Finch, NiCole, Crook, Richard, Baker, Matt, Desaro, Pamela, Johnston, Amelia, Rutherford, Nicola, Wojtas, Aleksandra, Kennelly, Kathleen, Wszolek, Zbigniew K., Graff-Radford, Neill, Boylan, Kevin, Rademakers, Rosa
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922682/
https://ncbi.nlm.nih.gov/pubmed/20232451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21241
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items