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Drosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functions

Reversible phosphoinositide phosphorylation provides a dynamic membrane code that balances opposing cell functions. However, in vivo regulatory relationships between specific kinases, phosphatases, and phosphoinositide subpools are not clear. We identified myotubularin (mtm), a Drosophila melanogast...

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Detalhes bibliográficos
Main Authors: Velichkova, Michaella, Juan, Joe, Kadandale, Pavan, Jean, Steve, Ribeiro, Inês, Raman, Vignesh, Stefan, Chris, Kiger, Amy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922644/
https://ncbi.nlm.nih.gov/pubmed/20696708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911020
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