Roles of epithelial cell-derived periostin in TGF-β activation, collagen production, and collagen gel elasticity in asthma

Periostin is considered to be a matricellular protein with expression typically confined to cells of mesenchymal origin. Here, by using in situ hybridization, we show that periostin is specifically up-regulated in bronchial epithelial cells of asthmatic subjects, and in vitro, we show that periostin...

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Detalhes bibliográficos
Main Authors: Sidhu, Sukhvinder S., Yuan, Shaopeng, Innes, Anh L., Kerr, Sheena, Woodruff, Prescott G., Hou, Lydia, Muller, Susan J., Fahy, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922596/
https://ncbi.nlm.nih.gov/pubmed/20660732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009426107
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