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Inducible response required for repair of low-dose radiation damage in human fibroblasts

Ionizing radiation (IR) induces a variety of DNA lesions among which DNA double-strand breaks (DSBs) are the biologically most significant. It is currently unclear if DSB repair is equally efficient after low and high doses. Here, we use γ-H2AX, phospho-ATM (pATM), and 53BP1 foci analysis to monitor...

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Bibliografiset tiedot
Päätekijät: Grudzenski, Saskia, Raths, Antonia, Conrad, Sandro, Rübe, Claudia E., Löbrich, Markus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922519/
https://ncbi.nlm.nih.gov/pubmed/20660770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002213107
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