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TRANSCRIPTIONAL PROFILES FOR GLUTAMATE TRANSPORTERS REVEAL DIFFERENCES BETWEEN ORGANOPHOSPHATES BUT SIMILARITIES WITH UNRELATED NEUROTOXICANTS

The developmental neurotoxicity of organophosphates involves mechanisms other than their shared property as cholinesterase inhibitors, among which are excitotoxicity and oxidative stress. We used PC12 cells as a neurodevelopmental model to compare the effects of chlorpyrifos and diazinon on the expr...

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Hlavní autoři: Slotkin, Theodore A., Lobner, Doug, Seidler, Frederic J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922476/
https://ncbi.nlm.nih.gov/pubmed/20600679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2010.06.010
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