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TRANSCRIPTIONAL PROFILES FOR GLUTAMATE TRANSPORTERS REVEAL DIFFERENCES BETWEEN ORGANOPHOSPHATES BUT SIMILARITIES WITH UNRELATED NEUROTOXICANTS

The developmental neurotoxicity of organophosphates involves mechanisms other than their shared property as cholinesterase inhibitors, among which are excitotoxicity and oxidative stress. We used PC12 cells as a neurodevelopmental model to compare the effects of chlorpyrifos and diazinon on the expr...

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Autori principali: Slotkin, Theodore A., Lobner, Doug, Seidler, Frederic J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922476/
https://ncbi.nlm.nih.gov/pubmed/20600679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2010.06.010
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