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Changes in mitochondrial functionality and calcium uptake in hypertensive rats as a function of age

We studied whether mitochondrial functions and Ca(2+) metabolism were altered in Wistar Kyoto normotensive (WKY) and spontaneous hypertensive rats (SHR). Ca(2+) uptake was decreased in SHR compared to WKY rats. Accumulation of Ca(2+) was more efficient in WKY than in SHR rats. mΔΨ was lower in SHR c...

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Detalhes bibliográficos
Main Authors: Calderón-Cortés, E., Cortés-Rojo, C., Clemente-Guerrero, M., Manzo-Ávalos, S., Villalobos-Molina, R., Boldogh, I., Saavedra-Molina, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922397/
https://ncbi.nlm.nih.gov/pubmed/18541459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2008.04.005
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