A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations

BACKGROUND: The development of novel influenza vaccines inducing a broad immune response is an important objective. The aim of this study was to evaluate live vaccines which induce both strong humoral and cell-mediated immune responses against the novel human pandemic H1N1 influenza virus, and to sh...

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Bibliographische Detailangaben
Hauptverfasser: Hessel, Annett, Schwendinger, Michael, Fritz, Daniela, Coulibaly, Sogue, Holzer, Georg W., Sabarth, Nicolas, Kistner, Otfried, Wodal, Walter, Kerschbaum, Astrid, Savidis-Dacho, Helga, Crowe, Brian A., Kreil, Thomas R., Barrett, P. Noel, Falkner, Falko G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922371/
https://ncbi.nlm.nih.gov/pubmed/20808939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012217
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