Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells

Our understanding of how mesodermal tissue is formed has been limited by the absence of specific and reliable markers of early mesoderm commitment. We report that mesoderm commitment from human embryonic stem cells (hESCs) is initiated by epithelial-to-mesenchymal transition (EMT) as shown by gene e...

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Bibliographic Details
Main Authors: Evseenko, Denis, Zhu, Yuhua, Schenke-Layland, Katja, Kuo, Jeffrey, Latour, Brooke, Ge, Shundi, Scholes, Jessica, Dravid, Gautam, Li, Xinmin, MacLellan, W. Robb, Crooks, Gay M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922221/
https://ncbi.nlm.nih.gov/pubmed/20643952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002077107
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