Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells

Our understanding of how mesodermal tissue is formed has been limited by the absence of specific and reliable markers of early mesoderm commitment. We report that mesoderm commitment from human embryonic stem cells (hESCs) is initiated by epithelial-to-mesenchymal transition (EMT) as shown by gene e...

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Bibliografiske detaljer
Main Authors: Evseenko, Denis, Zhu, Yuhua, Schenke-Layland, Katja, Kuo, Jeffrey, Latour, Brooke, Ge, Shundi, Scholes, Jessica, Dravid, Gautam, Li, Xinmin, MacLellan, W. Robb, Crooks, Gay M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922221/
https://ncbi.nlm.nih.gov/pubmed/20643952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002077107
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