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Metacaspase Yca1 is required for clearance of insoluble protein aggregates

In complex organisms, caspase proteases mediate a variety of cell behaviors, including proliferation, differentiation, and programmed cell death/apoptosis. Structural homologs to the caspase family (termed metacaspases) engage apoptosis in single-cell eukaryotes, yet the molecular mechanisms that co...

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Detalles Bibliográficos
Autores principales: Lee, Robin E. C., Brunette, Steve, Puente, Lawrence G., Megeney, Lynn A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922170/
https://ncbi.nlm.nih.gov/pubmed/20624963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006610107
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