Role of COX-2 in cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome

BACKGROUND: Sinobronchial syndrome is a cause of chronic productive cough. Inflammatory mediators are involved in the pathophysiology of chronic productive cough. Accumulating evidences indicate that cyclooxygenase (COX)-2, one of the inducible isoforms of COX, is a key element in the pathophysiolog...

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Bibliografiske detaljer
Main Authors: Ishiura, Yoshihisa, Fujimura, Masaki, Yamamoto, Hiroki, Ohkura, Noriyuki, Myou, Shigeharu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922077/
https://ncbi.nlm.nih.gov/pubmed/20696045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-9974-6-7
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