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The Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein

In response to stress p53 initiates the transcriptional regulation of selected target genes and various cellular responses, including cell cycle arrest, apoptosis and senescence. Recent studies revealed two additional functions of p53 in regulation of IGF-1/AKT/mTOR pathways and energy metabolism, w...

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Detalhes bibliográficos
Main Authors: Feng, Zhaohui, Levine, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921989/
https://ncbi.nlm.nih.gov/pubmed/20399660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2010.03.004
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