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Modulation of Mitochondrial Proteome and Improved Mitochondrial Function by Biventricular Pacing of Dyssynchronous Failing Hearts

BACKGROUND: Cardiac resynchronization therapy (CRT) improves chamber mechanoenergetics and morbidity and mortality of patients manifesting heart failure with ventricular dyssynchrony; however, little is known about the molecular changes underlying CRT benefits. We hypothesized that mitochondria may...

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Detalhes bibliográficos
Main Authors: Agnetti, Giulio, Kaludercic, Nina, Kane, Lesley A., Elliott, Steven T., Guo, Yurong, Chakir, Khalid, Samantapudi, Daya, Paolocci, Nazareno, Tomaselli, Gordon F., Kass, David A., Van Eyk, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921909/
https://ncbi.nlm.nih.gov/pubmed/20160199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.109.871236
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