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α-Phenyl-n-tert-butyl-nitrone Attenuates Lipopolysaccharide-induced Brain Injury and Improves Neurological Reflexes and Early Sensorimotor Behavioral Performance in Juvenile Rats

Our previous study showed that treatment with α-phenyl-n-tert-butyl-nitrone (PBN) after exposure to lipopolysaccharide (LPS) reduced LPS-induced white matter injury in the neonatal rat brain. The object of the current study was to further examine whether PBN has long-lasting protective effects and a...

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Autors principals: Fan, Lir-Wan, Chen, Ruei-Feng, Mitchell, Helen J., Lin, Rick C. S., Simpson, Kimberly L., Rhodes, Philip G., Cai, Zhengwei
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921906/
https://ncbi.nlm.nih.gov/pubmed/18683243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21812
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