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Isolation and translation of hemoglobin messenger RNA from thalassemia, sickle cell anemia, and normal human reticulocytes

Human hemoglobin messenger RNA was isolated by sucrose gradient centrifugation from reticulocytes of patients having various hemolytic anemias. Using a messenger RNA-dependent cell-free system derived entirely from rabbit reticulocytes, the human hemoglobin messenger RNA has been translated and the...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Nienhuis, Arthur W., Anderson, W. French
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1971
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292189/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5096528/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106745
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