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Hemoglobin Louisville (β42 (CD1) Phe→Leu): an unstable variant causing mild hemolytic anemia

An unstable hemoglobin variant termed Hb Louisville, was found in four members of a Caucasian family, who were suffering from a mild hemolytic anemia. The variant showed a decreased stability upon warming at 65°C and an increased tendency to dissociate in the presence of sulfhydryl group-blocking ag...

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Publicado en:J Clin Invest
Principais autores: Keeling, Marie M., Ogden, Lynn L., Wrightstone, Ruth N., Wilson, J. B., Reynolds, Cecelia A., Kitchens, Janice L., Huisman, T. H. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1971
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5096522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106738
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