Protocol for PTEN Expression by Immunohistochemistry in Formalin-fixed Paraffin-embedded Human Breast Carcinoma

The PI3K/PTEN pathway plays a major role in carcinogenesis. Dysregulation of this pathway occurs frequently in breast cancer, and loss of PTEN expression is emerging as a potentially important mechanism of resistance to the widely used anti-HER2 therapy, trastuzumab. However, assays for loss of PTEN...

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Hauptverfasser: Sakr, Rita A., Barbashina, Violetta, Morrogh, Mary, Chandarlapaty, Sarat, Andrade, Victor P., Arroyo, Crispinita D., Olvera, Narciso, King, Tari A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921801/
https://ncbi.nlm.nih.gov/pubmed/20216404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0b013e3181d50bd5
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