Polymorphic Variants of LIGHT (TNF Superfamily-14) Alter Receptor Avidity and Bioavailability

The TNF superfamily member, LIGHT (TNFSF14) is a key cytokine that activates T cells and dendritic cells, and is implicated as a mediator of inflammatory, metabolic and malignant diseases. LIGHT engages the Lymphotoxin-β receptor (LTβR) and herpesvirus entry mediator (HVEM, TNFRSF14), but is competi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Cheung, Timothy C., Coppieters, Ken, Sanjo, Hideki, Oborne, Lisa M., Norris, Paula S., Coddington, Amy, Granger, Steven W., Elewaut, Dirk, Ware, Carl F.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921593/
https://ncbi.nlm.nih.gov/pubmed/20592286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001159
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker