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Hydrogen peroxide utilization in myeloperoxidase-deficient leukocytes: a possible microbicidal control mechanism

Phagocytosis-induced formate and glucose C-1 oxidation by the polymorphonuclear leukocytes of a patient with hereditary myeloperoxidase deficiency was considerably greater than normal. The addition of catalase to the leukocyte suspension was required for optimum formate oxidation. Azide and cyanide...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Klebanoff, Seymour J., Pincus, Stephanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292158/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5116211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106718
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