Screening for germline DND1 mutations in testicular cancer patients

Although several observations suggest that a strong genetic predisposition to developing testicular germ cell tumors (TGCT) exists, no associated, highly penetrant germline mutations have been identified so far. In the 129/Sv mouse strain, a germline mutation in the DND1 gene has been shown to stron...

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Autores principales: Sijmons, Rolf H., Vos, Yvonne J., Herkert, Johanna C., Bos, Krista K., Holzik, Martijn F. Lutke, Hoekstra-Weebers, Josette E. H. M., Hofstra, Robert M. W., Hoekstra, Harald J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921500/
https://ncbi.nlm.nih.gov/pubmed/20411342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-010-9340-y
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