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Surfactant Protein-C Promoter Variants Associated with Neonatal Respiratory Distress Syndrome Reduce Transcription

Dominant mutations in coding regions of the surfactant protein-C gene (SFTPC) cause respiratory distress syndrome (RDS) in infants. However, the contribution of variants in noncoding regions of SFTPC to pulmonary phenotypes is unknown. Using a case-control group of infants ≥34 weeks gestation (n=538...

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Detalhes bibliográficos
Main Authors: Wambach, Jennifer A., Yang, Ping, Wegner, Daniel J., An, Ping, Hackett, Brian P., Cole, F. S., Hamvas, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921462/
https://ncbi.nlm.nih.gov/pubmed/20539253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181eb5d68
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