Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism

We have recently identified and characterized NADPH-dependent microsomal heme oxygenase as the major enzymatic mechanism for the conversion of hemoglobin-heme to bilirubin-IXα in vivo. Enzyme activity is highest in tissues normally involved in red cell breakdown, that is, spleen, liver, and bone mar...

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Bibliografische Detailangaben

Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Pimstone, Neville R., Engel, Peter, Tenhunen, Raimo, Seitz, Paul T., Marver, Harvey S., Schmid, Rudi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1971
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4398936/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106697
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