The Imprinted Gene Neuronatin Is Regulated by Metabolic Status and Associated With Obesity

Using restriction fragment differential display (RFDD) technology, we have identified the imprinted gene neuronatin (Nnat) as a hypothalamic target under the influence of leptin. Nnat mRNA expression is decreased in several key appetite regulatory hypothalamic nuclei in rodents with impaired leptin...

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Detalhes bibliográficos
Main Authors: Vrang, Niels, Meyre, David, Froguel, Phillippe, Jelsing, Jacob, Tang-Christensen, Mads, Vatin, Vincent, Mikkelsen, Jens D., Thirstrup, Kenneth, Larsen, Leif K., Cullberg, Karina B., Fahrenkrug, Jan, Jacobson, Per, Sjöström, Lars, Carlsson, Lena M.S., Liu, Yongjun, Liu, Xiaogang, Deng, Hong-Wen, Larsen, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921166/
https://ncbi.nlm.nih.gov/pubmed/19851307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.361
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