DNA damage and estrogenic activity induced by the environmental pollutant 2-nitrotoluene and its metabolite

OBJECTIVES: The environmental pollutant 2-nitrotoluene (2-NO(2)-T) is carcinogenic and reproductively toxic in animals. In this study, we elucidated the mechanisms of its carcinogenicity and reproductive toxicity. METHODS: We examined DNA damage induced by 2-NO(2)-T and its metabolite, 2-nitrosotolu...

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Detalhes bibliográficos
Main Authors: Watanabe, Chigusa, Egami, Takashi, Midorikawa, Kaoru, Hiraku, Yusuke, Oikawa, Shinji, Kawanishi, Shosuke, Murata, Mariko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2010
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921039/
https://ncbi.nlm.nih.gov/pubmed/21432561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12199-010-0146-1
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