Bacteriophage Lysin Mediates the Binding of Streptococcus mitis to Human Platelets through Interaction with Fibrinogen

The binding of bacteria to human platelets is a likely central mechanism in the pathogenesis of infective endocarditis. We have previously found that platelet binding by Streptococcus mitis SF100 is mediated by surface components encoded by a lysogenic bacteriophage, SM1. We now demonstrate that SM1...

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Bibliographic Details
Main Authors: Seo, Ho Seong, Xiong, Yan Q., Mitchell, Jennifer, Seepersaud, Ravin, Bayer, Arnold S., Sullam, Paul M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920869/
https://ncbi.nlm.nih.gov/pubmed/20714354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001047
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