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Mechanism of Cohesin Loading onto Chromosomes: A Conformational Dynamics Study

The structure-function relationship of cohesin, an essential chromosome maintenance protein, is investigated by analyzing its collective dynamics and conformational flexibility, enhancing our understanding of the sister chromatid cohesion process. A three-dimensional model of cohesin has been constr...

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Detalhes bibliográficos
Main Authors: Kurkcuoglu, Ozge, Bates, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920725/
https://ncbi.nlm.nih.gov/pubmed/20713005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.006
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