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A Molecular Dynamics Investigation of Vinculin Activation
Vinculin activation plays a critical role in focal adhesion initiation and formation. In its native state, vinculin is in an autoinhibitory conformation in which domain 1 prevents interaction of the vinculin tail domain with actin by steric hindrance. Once activated, vinculin is able to interact wit...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920635/ https://ncbi.nlm.nih.gov/pubmed/20712990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.024 |
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