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Thermal and Structural Stability of Adsorbed Proteins

Experimental evidence suggests that proteins adsorbed to hydrophobic surfaces at low coverages are stabilized relative to the bulk. For larger coverages, proteins unfold and form β-sheets. We performed computer simulations on model proteins and found that: 1), For weakly adsorbing surfaces, unfolded...

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Detalhes bibliográficos
Main Authors: Sharma, Sumit, Berne, B.J., Kumar, Sanat K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920629/
https://ncbi.nlm.nih.gov/pubmed/20712999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.030
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