Age-Related Changes in Scavenger Receptor–Mediated Endocytosis in Rat Liver Sinusoidal Endothelial Cells

Liver sinusoidal endothelial cells (LSECs) play an essential role in systemic waste clearance by effective endocytosis of blood-borne waste macromolecules. We aimed to study LSECs’ scavenger function during aging, and whether age-related morphological changes (eg, defenestration) affect this functio...

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Detalhes bibliográficos
Main Authors: Simon-Santamaria, Jaione, Malovic, Ivana, Warren, Alessandra, Oteiza, Ana, Le Couteur, David, Smedsrød, Bård, McCourt, Peter, Sørensen, Karen Kristine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Journal of Gerontology: BIOLOGICAL SCIENCES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920583/
https://ncbi.nlm.nih.gov/pubmed/20576648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq108
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