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Principal Component Analysis of HPLC Retention Data and Molecular Modeling Structural Parameters of Cardiovascular System Drugs in View of Their Pharmacological Activity

Evaluation of relationships between molecular modeling structural parameters and high-performance liquid chromatography (HPLC) retention data of 11 cardiovascular system drugs by principal component analysis (PCA) in relation to their pharmacological activity was performed. The six retention data pa...

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Detalhes bibliográficos
Main Authors: Stasiak, Jolanta, Koba, Marcin, Bober, Leszek, Bączek, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920560/
https://ncbi.nlm.nih.gov/pubmed/20717530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11072681
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