High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA

The DrrA protein of Legionella pneumophila is involved in mistargeting of endoplasmic reticulum-derived vesicles to Legionella-containing vacuoles through recruitment of the small GTPase Rab1. To this effect, DrrA binds specifically to phosphatidylinositol 4-phosphate (PtdIns(4)P) lipids on the cyto...

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Autores principales: Schoebel, Stefan, Blankenfeldt, Wulf, Goody, Roger S, Itzen, Aymelt
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920447/
https://ncbi.nlm.nih.gov/pubmed/20616805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.97
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