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A Minimal Model of Signaling Network Elucidates Cell-to-Cell Stochastic Variability in Apoptosis

BACKGROUND: Signaling networks are designed to sense an environmental stimulus and adapt to it. We propose and study a minimal model of signaling network that can sense and respond to external stimuli of varying strength in an adaptive manner. The structure of this minimal network is derived based o...

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Detalhes bibliográficos
Autor principal: Raychaudhuri, Subhadip
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920308/
https://ncbi.nlm.nih.gov/pubmed/20711445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011930
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