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Structural basis of Fic mediated adenylylation

The Fic family of adenylyltransferases, defined by a core HPFx(D/E)GN(G/K)R motif, consist of over 2700 proteins found from bacteria to humans. IbpA from the bacterial pathogen Histophilus somni contains two Fic domains that adenylylate the switch1 Tyr residue of Rho-family GTPases, allowing the bac...

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Autors principals: Xiao, Junyu, Worby, Carolyn A., Mattoo, Seema, Sankaran, Banumathi, Dixon, Jack E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920259/
https://ncbi.nlm.nih.gov/pubmed/20622875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1867
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