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Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

Here, we describe a simple micromolding method to construct three-dimensional arrays of organotypic epithelial tissue structures that approximate in vivo histology. An elastomeric stamp containing an array of posts of defined geometry and spacing is used to mold microscale cavities into the surface...

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Autori principali: Nelson, Celeste M, Inman, Jamie L, Bissell, Mina J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920258/
https://ncbi.nlm.nih.gov/pubmed/18388950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2008.35
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